Impaired Fasting Glucose and Risk of Cardiovascular Disease in Korean Men andWomen The Korean Heart Study

RESULTSdIncidence rates of CVD (per 100,000 person-years) were 2,203 for diabetes. Ageadjusted hazard ratios (HRs) for CVDwere 1.17 (95%CI 1.13–1.20) for grade 1 IFG, 1.30 (1.24– 1.35) for grade 2 IFG, and 1.81 (1.75–1.86) for diabetes. The increased risk for women was similar to that of men. Age-adjusted HRs for IHD and ischemic stroke were also significantly increased for men and women with IFG and diabetes. After multivariate adjustment of conventional risk factors (hypertension, dyslipidemia, smoking, obesity, and family history of CVD), the overall risk of CVD was greatly attenuated in all categories. However, the HRs for IHD and ischemic stroke remained significantly increased in men for grade 2 IFG but not in women.